Cargando…

Targeting the extradomain A of fibronectin allows identification of vascular resistance to antiangiogenic therapy in experimental glioma

INTRODUCTION: Clinical application of antiangiogenic therapy lacks direct visualization of therapy efficacy and vascular resistance. We aimed to establish molecular imaging during treatment with sunitinib using the fibronectin extradomain A specific small immunoprotein(SIP)-F8 in glioma. METHODS: Bi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Acker, Güliz, Piper, Sophie Käthe, Datwyler, Anna Lena, Broggini, Thomas, Kremenetskaia, Irina, Nieminen-Kelhä, Melina, Lips, Janet, Harms, Ulrike, Mueller, Susanne, Lättig-Tünnemann, Gilla, Trachsel, Eveline, Palumbo, Alessandro, Neri, Dario, Klohs, Jan, Endres, Matthias, Vajkoczy, Peter, Harms, Christoph, Czabanka, Marcus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021244/ https://www.ncbi.nlm.nih.gov/pubmed/29963235 http://dx.doi.org/10.18632/oncotarget.25570

Ejemplares similares

EphB4 mediates resistance to antiangiogenic therapy in experimental glioma
por: Uhl, Christian, et al.
Publicado: (2018)

RNA-Seq Analysis of Extradomain A and Extradomain B Fibronectin as Extracellular Matrix Markers for Cancer
por: Hall, Ryan C., et al.
Publicado: (2023)

Overexpression of Extradomain-B Fibronectin is Associated with Invasion of Breast Cancer Cells
por: Vaidya, Amita, et al.
Publicado: (2020)

SUMO2/3 conjugation is an endogenous neuroprotective mechanism
por: Datwyler, Anna Lena, et al.
Publicado: (2011)

The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice
por: Román, Beatriz San, et al.
Publicado: (2012)

Ultrasound Molecular Imaging of Bladder Cancer via Extradomain B Fibronectin-Targeted Biosynthetic GVs
por: Feng, Yanan, et al.
Publicado: (2023)

Passive Entrapment of Tumor Cells Determines Metastatic Dissemination to Spinal Bone and Other Osseous Tissues
por: Broggini, Thomas, et al.
Publicado: (2016)

Ligand-Dependent and Ligand-Independent Effects of Ephrin-B2–EphB4 Signaling in Melanoma Metastatic Spine Disease
por: Piffko, Andras, et al.
Publicado: (2021)

Magnetic Resonance Molecular Imaging of Extradomain B Fibronectin Improves Imaging of Pancreatic Cancer Tumor Xenografts
por: Qiao, Peter, et al.
Publicado: (2020)

Noninvasive assessment and therapeutic monitoring of drug-resistant colorectal cancer by MR molecular imaging of extradomain-B fibronectin
por: Vaidya, Amita, et al.
Publicado: (2020)

The CXCL2/IL8/CXCR2 Pathway Is Relevant for Brain Tumor Malignancy and Endothelial Cell Function
por: Urbantat, Ruth M., et al.
Publicado: (2021)

Tumor-Associated Microglia/Macrophages as a Predictor for Survival in Glioblastoma and Temozolomide-Induced Changes in CXCR2 Signaling with New Resistance Overcoming Strategy by Combination Therapy
por: Urbantat, Ruth M., et al.
Publicado: (2021)

Microglia as target for anti-inflammatory approaches to prevent secondary brain injury after subarachnoid hemorrhage (SAH)
por: Heinz, Rebecca, et al.
Publicado: (2021)

Uncoupling the Excitatory Amino Acid Transporter 2 From Its C-Terminal Interactome Restores Synaptic Glutamate Clearance at Corticostriatal Synapses and Alleviates Mutant Huntingtin-Induced Hypokinesia
por: Hirschberg, Stefan, et al.
Publicado: (2022)

Establishment and Validation of CyberKnife Irradiation in a Syngeneic Glioblastoma Mouse Model
por: Jelgersma, Claudius, et al.
Publicado: (2021)

Zfp580 inactivation as a new therapeutic target to enhance recovery after stroke in mice
por: Hoffmann, Christian J, et al.
Publicado: (2023)

Role of mTOR and VEGFR Inhibition in Prevention of Metastatic Tumor Growth in the Spine
por: Kratzsch, Tobias, et al.
Publicado: (2020)

EphrinB2–EphB4 Signaling in Neurooncological Disease
por: Piffko, Andras, et al.
Publicado: (2022)

Three-Dimensional Iron Oxide Nanoparticle-Based Contrast-Enhanced Magnetic Resonance Imaging for Characterization of Cerebral Arteriogenesis in the Mouse Neocortex
por: de Bortoli, Till, et al.
Publicado: (2021)

Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress
por: Jochner, Magdalena C. E., et al.
Publicado: (2019)

Endothelial EphrinB2 Regulates Sunitinib Therapy Response in Murine Glioma
por: Broggini, Thomas, et al.
Publicado: (2022)

LPPR5 Expression in Glioma Affects Growth, Vascular Architecture, and Sunitinib Resistance
por: Stange, Lena, et al.
Publicado: (2022)

Resolution of Cerebral Inflammation Following Subarachnoid Hemorrhage
por: Patsouris, Victor, et al.
Publicado: (2023)

Vascular Endothelial Growth Factor Augments the Tolerance Towards Cerebral Stroke by Enhancing Neurovascular Repair Mechanism
por: Ghori, Adnan, et al.
Publicado: (2022)

Influence of Pigment Epithelium-Derived Factor on Outcome after Striatal Cerebral Ischemia in the Mouse
por: Zille, Marietta, et al.
Publicado: (2014)

Surgical Management of Failed Revascularization in Moyamoya Vasculopathy
por: Lucia, Kristin, et al.
Publicado: (2021)

The Development and Effect of Systemic Hypertension on Clinical and Radiological Outcome in Adult Moyamoya Angiopathy Following Revascularization Surgery: Experience of a Single European Institution
por: Lucia, Kristin, et al.
Publicado: (2023)

In vivo imaging in experimental spinal cord injury – Techniques and trends
por: Hubertus, Vanessa, et al.
Publicado: (2021)

Minocycline Attenuates Microglia/Macrophage Phagocytic Activity and Inhibits SAH-Induced Neuronal Cell Death and Inflammation
por: Blecharz-Lang, Kinga G., et al.
Publicado: (2022)

Zfp580 Regulates Paracrine and Endocrine Igf1 and Igfbp3 Differently in the Brain and Blood After a Murine Stroke
por: Hoffmann, Christian J., et al.
Publicado: (2022)

A novel cell permeable DNA replication and repair marker
por: Herce, Henry D, et al.
Publicado: (2014)

Antiangiogenic activity of aplidine, a new agent of marine origin
por: Taraboletti, G, et al.
Publicado: (2004)

Clinical implementation of a 3D4K-exoscope (Orbeye) in microneurosurgery
por: Rösler, Judith, et al.
Publicado: (2021)

Personalized surgical informed consent with stereoscopic visualization in neurosurgery—real benefit for the patient or unnecessary gimmick?
por: Hertzsprung, Nicolas, et al.
Publicado: (2023)

CCR2 of Tumor Microenvironmental Cells Is a Relevant Modulator of Glioma Biology
por: Felsenstein, Matthäus, et al.
Publicado: (2020)

Certain types of iron oxide nanoparticles are not suited to passively target inflammatory cells that infiltrate the brain in response to stroke
por: Harms, Christoph, et al.
Publicado: (2013)

Principles of protein targeting to the nucleolus
por: Martin, Robert M, et al.
Publicado: (2015)

Antiangiogenic therapy
por: Avitabile, T
Publicado: (2010)

Validation of the Berlin Grading System for moyamoya angiopathy with the use of [(15)O]H(2)O PET
por: Mertens, R., et al.
Publicado: (2022)

Low-dose rapamycin does not impair vascular integrity and tubular regeneration after kidney transplantation in rats
por: Hoff, Uwe, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rflusu8njbl6re9kvufp3bch72