Cargando…
The small molecule STF-62247 induces apoptotic and autophagic cell death in leukemic cells
Adult T cell leukemia/lymphoma (ATL) is an aggressive malignant T cell disease caused by human T cell leukemia virus-I (HTLV-1). Treatment outcomes for aggressive subtypes of ATL remain poor, with little improvement in overall survival since HTLV-1 was discovered. Therefore, new therapeutic strategi...
Autores principales: | Kozako, Tomohiro, Sato, Keisuke, Uchida, Yuichiro, Kato, Naho, Aikawa, Akiyoshi, Ogata, Kentaro, Kamimura, Hidetoshi, Uemura, Haruna, Yoshimitsu, Makoto, Ishitsuka, Kenji, Higaki, Yasuki, Tanaka, Hiroaki, Honda, Shin-Ichiro, Soeda, Shinji |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021257/ https://www.ncbi.nlm.nih.gov/pubmed/29963226 http://dx.doi.org/10.18632/oncotarget.25291 |
Ejemplares similares
-
STF-62247 and pimozide induce autophagy and autophagic cell death in mouse embryonic fibroblasts
por: Kinzler, Maximilian N., et al.
Publicado: (2020) -
Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells
por: Zielke, Svenja, et al.
Publicado: (2018) -
A novel small-molecule SIRT1 inhibitor induces apoptosis in leukemic cell lines
por: Kozako, Tomohiro, et al.
Publicado: (2014) -
Decrease of Intracellular Glutamine by STF-62247 Results in the Accumulation of Lipid Droplets in von Hippel-Lindau Deficient Cells
por: Johnson, Mathieu, et al.
Publicado: (2022) -
Novel small-molecule SIRT1 inhibitors induce cell death in adult T-cell leukaemia cells
por: Kozako, Tomohiro, et al.
Publicado: (2015)