The combination of everolimus and zoledronic acid increase the efficacy of gemcitabine in a mouse model of pancreatic adenocarcinoma

BACKGROUND: Gemcitabine is a standard treatment for pancreatic adenocarcinoma. Many mechanisms are involved in gemcitabine resistance, such as reduced expression of the human equilibrative nucleoside transporter 1 (hENT1) membrane transporter, deoxycytidine kinase deficiency, and changes in the sign...

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Detalles Bibliográficos
Autores principales: Vitellius, Carole, Fizanne, Lionel, Menager-Tabourel, Elodie, Nader, Joelle, Baize, Nathalie, Laly, Margot, Lermite, Emilie, Bertrais, Sandrine, Caroli-Bosc, FX
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021353/
https://www.ncbi.nlm.nih.gov/pubmed/29963262
http://dx.doi.org/10.18632/oncotarget.25560

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