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Reducing histone acetylation rescues cognitive deficits in a mouse model of Fragile X syndrome

Fragile X syndrome (FXS) is the most prevalent inherited intellectual disability, resulting from a loss of fragile X mental retardation protein (FMRP). Patients with FXS suffer lifelong cognitive disabilities, but the function of FMRP in the adult brain and the mechanism underlying age-related cogni...

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Detalles Bibliográficos
Autores principales:	Li, Yue, Stockton, Michael E., Eisinger, Brian E., Zhao, Yinghua, Miller, Jessica L., Bhuiyan, Ismat, Gao, Yu, Wu, Zhiping, Peng, Junmin, Zhao, Xinyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021376/ https://www.ncbi.nlm.nih.gov/pubmed/29950602 http://dx.doi.org/10.1038/s41467-018-04869-3

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