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Serotonin and YAP/VGLL4 Balance Correlated with Progression and Poor Prognosis of Hepatocellular Carcinoma

YAP-TEAD complex plays an important role in tumorigenesis. 5-HT is proved to upregulate YAP expression by our previous study and VGLL4 is found to compete with YAP for binding to TEAD in several of cancers. Here, we investigated whether 5-HT could affect progression and prognosis of hepatocellular c...

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Detalles Bibliográficos
Autores principales:	Shu, Bo, Zhai, Mimi, Miao, Xiongying, He, Chao, Deng, Chaolin, Fang, Yu, Luo, Ming, Liu, Luyao, Liu, Sushun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021381/ https://www.ncbi.nlm.nih.gov/pubmed/29950605 http://dx.doi.org/10.1038/s41598-018-28075-9

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