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Endoplasmic Reticulum Stress Mediated MDRV p10.8 Protein-Induced Cell Cycle Arrest and Apoptosis Through the PERK/eIF2α Pathway

In this study, the mechanism of Muscovy duck reovirus (MDRV) p10.8 protein-induced pathogenesis was investigated, with a focus on endoplasmic reticulum (ER) stress. In chicken embryo fibroblasts cell lines (DF1), pCI-neo-flg-p10.8 protein transfection increased the phosphorylation (p-) levels of PER...

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Detalles Bibliográficos
Autores principales:	Wang, Quanxi, Yuan, Xiaoqin, Chen, Yuan, Zheng, Qingli, Xu, Lihui, Wu, Yijian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021497/ https://www.ncbi.nlm.nih.gov/pubmed/29977231 http://dx.doi.org/10.3389/fmicb.2018.01327

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