Cargando…
In Vitro Evolution of Antibodies Inspired by In Vivo Evolution
In vitro generation of antibodies often requires variable domain sequence evolution to adapt the protein in terms of affinity, specificity, or developability. Such antibodies, including those that are of interest for clinical development, may have their origins in a diversity of immunoglobulin germl...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021498/ https://www.ncbi.nlm.nih.gov/pubmed/29977238 http://dx.doi.org/10.3389/fimmu.2018.01391 |