The Enzymatic Core of the Parkinson’s Disease-Associated Protein LRRK2 Impairs Mitochondrial Biogenesis in Aging Yeast

Mitochondrial dysfunction is a prominent trait of cellular decline during aging and intimately linked to neuronal degeneration during Parkinson’s disease (PD). Various proteins associated with PD have been shown to differentially impact mitochondrial dynamics, quality control and function, including...

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Detalles Bibliográficos
Autores principales: Aufschnaiter, Andreas, Kohler, Verena, Walter, Corvin, Tosal-Castano, Sergi, Habernig, Lukas, Wolinski, Heimo, Keller, Walter, Vögtle, F.-Nora, Büttner, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021522/
https://www.ncbi.nlm.nih.gov/pubmed/29977190
http://dx.doi.org/10.3389/fnmol.2018.00205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021522/
https://www.ncbi.nlm.nih.gov/pubmed/29977190
http://dx.doi.org/10.3389/fnmol.2018.00205

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