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CRISPR/Cas9-mediated knock-in of the murine Y chromosomal Sry gene

Mammalian zygote-mediated genome editing via the clustered regularly interspaced short palindromic repeats/CRISPR-associated endonuclease 9 (CRISPR/Cas9) system is widely used to generate genome-modified animals. This system allows for the production of loss-of-function mutations in various Y chromo...

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Detalles Bibliográficos
Autores principales:	IMAIMATSU, Kenya, FUJII, Wataru, HIRAMATSU, Ryuji, MIURA, Kento, KUROHMARU, Masamichi, KANAI, Yoshiakira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Society for Reproduction and Development 2018
Materias:	Technology Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021606/ https://www.ncbi.nlm.nih.gov/pubmed/29657232 http://dx.doi.org/10.1262/jrd.2017-161

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