The first report of terbinafine resistance Microsporum canis from a cat

A 2-year-old, exotic shorthair cat presented with baldness and mild scaling on trunk that was confirmed as Microsporum canis (M. canis) infection by the following methods. Wood’s lamp and trichogram were used to demonstrate fungal elements suggestive of dermatophytosis consistent with M. canis. Derm...

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Autores principales: HSIAO, Yun-Hsia, CHEN, Charles, HAN, Hock Siew, KANO, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2018
Materias:
Public Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021895/
https://www.ncbi.nlm.nih.gov/pubmed/29657238
http://dx.doi.org/10.1292/jvms.17-0680
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author HSIAO, Yun-Hsia
CHEN, Charles
HAN, Hock Siew
KANO, Rui
author_facet HSIAO, Yun-Hsia
CHEN, Charles
HAN, Hock Siew
KANO, Rui
author_sort HSIAO, Yun-Hsia
collection PubMed
description A 2-year-old, exotic shorthair cat presented with baldness and mild scaling on trunk that was confirmed as Microsporum canis (M. canis) infection by the following methods. Wood’s lamp and trichogram were used to demonstrate fungal elements suggestive of dermatophytosis consistent with M. canis. Dermatophyte test medium (DTM) and polymerase chain reaction (PCR) were used for identification. E-test and broth microdilution test were then utilized to estimate antifungal minimal inhibitory concentrations (MICs) towards ITZ and TRF respectively. The strain was isolated from the patient and revealed TRF MIC >32 µg/ml and ITZ MIC 0.023 µg/ml. Patient was cured of dermatophytosis with systemic ITZ.
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spelling pubmed-60218952018-07-06 The first report of terbinafine resistance Microsporum canis from a cat HSIAO, Yun-Hsia CHEN, Charles HAN, Hock Siew KANO, Rui J Vet Med Sci Public Health A 2-year-old, exotic shorthair cat presented with baldness and mild scaling on trunk that was confirmed as Microsporum canis (M. canis) infection by the following methods. Wood’s lamp and trichogram were used to demonstrate fungal elements suggestive of dermatophytosis consistent with M. canis. Dermatophyte test medium (DTM) and polymerase chain reaction (PCR) were used for identification. E-test and broth microdilution test were then utilized to estimate antifungal minimal inhibitory concentrations (MICs) towards ITZ and TRF respectively. The strain was isolated from the patient and revealed TRF MIC >32 µg/ml and ITZ MIC 0.023 µg/ml. Patient was cured of dermatophytosis with systemic ITZ. The Japanese Society of Veterinary Science 2018-04-16 2018-06 /pmc/articles/PMC6021895/ /pubmed/29657238 http://dx.doi.org/10.1292/jvms.17-0680 Text en ©2018 The Japanese Society of Veterinary Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Public Health
HSIAO, Yun-Hsia
CHEN, Charles
HAN, Hock Siew
KANO, Rui
The first report of terbinafine resistance Microsporum canis from a cat
title The first report of terbinafine resistance Microsporum canis from a cat
title_full The first report of terbinafine resistance Microsporum canis from a cat
title_fullStr The first report of terbinafine resistance Microsporum canis from a cat
title_full_unstemmed The first report of terbinafine resistance Microsporum canis from a cat
title_short The first report of terbinafine resistance Microsporum canis from a cat
title_sort first report of terbinafine resistance microsporum canis from a cat
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021895/
https://www.ncbi.nlm.nih.gov/pubmed/29657238
http://dx.doi.org/10.1292/jvms.17-0680
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