Cargando…
A Young Male with Severe Myocarditis and Skeletal Muscle Myositis
A 34-year-old male presented with retrosternal chest pain, fatigue, shortness of breath, and a history of a previous episode of myocarditis four years prior. He had elevated troponin T, normal skeletal muscle enzymes, and negative inflammatory markers. Cardiac magnetic resonance imaging (MRI) confir...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022326/ https://www.ncbi.nlm.nih.gov/pubmed/30013801 http://dx.doi.org/10.1155/2018/5698739 |
_version_ | 1783335655707770880 |
---|---|
author | Ibrahim, Abdalla Meagher, Eoghan Fraser, Alexander Kiernan, Thomas J. |
author_facet | Ibrahim, Abdalla Meagher, Eoghan Fraser, Alexander Kiernan, Thomas J. |
author_sort | Ibrahim, Abdalla |
collection | PubMed |
description | A 34-year-old male presented with retrosternal chest pain, fatigue, shortness of breath, and a history of a previous episode of myocarditis four years prior. He had elevated troponin T, normal skeletal muscle enzymes, and negative inflammatory markers. Cardiac magnetic resonance imaging (MRI) confirmed active myocarditis with extensive myocardial fibrosis and normal left ventricular ejection fraction (LVEF). His myocarditis symptoms resolved with steroids and anti-inflammatory treatment, but on closer questioning, he reported a vague history of long-standing calf discomfort associated with episodes of stiffness, fatigue, and flu-like symptoms. MRI of the lower legs consequently demonstrated active myositis in the calf muscles. Immunomodulatory therapy was commenced with good effect. The patient is undergoing regular follow-up in both cardiology and rheumatology outpatient departments. Repeated MRI of the legs showed significant interval improvement in his skeletal muscle myositis, and repeat cardiac MRI demonstrated the resolution of myocarditis along with persistent stable extensive myocardial fibrosis and preserved LVEF. The patient has returned to full-time work. |
format | Online Article Text |
id | pubmed-6022326 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-60223262018-07-16 A Young Male with Severe Myocarditis and Skeletal Muscle Myositis Ibrahim, Abdalla Meagher, Eoghan Fraser, Alexander Kiernan, Thomas J. Case Rep Cardiol Case Report A 34-year-old male presented with retrosternal chest pain, fatigue, shortness of breath, and a history of a previous episode of myocarditis four years prior. He had elevated troponin T, normal skeletal muscle enzymes, and negative inflammatory markers. Cardiac magnetic resonance imaging (MRI) confirmed active myocarditis with extensive myocardial fibrosis and normal left ventricular ejection fraction (LVEF). His myocarditis symptoms resolved with steroids and anti-inflammatory treatment, but on closer questioning, he reported a vague history of long-standing calf discomfort associated with episodes of stiffness, fatigue, and flu-like symptoms. MRI of the lower legs consequently demonstrated active myositis in the calf muscles. Immunomodulatory therapy was commenced with good effect. The patient is undergoing regular follow-up in both cardiology and rheumatology outpatient departments. Repeated MRI of the legs showed significant interval improvement in his skeletal muscle myositis, and repeat cardiac MRI demonstrated the resolution of myocarditis along with persistent stable extensive myocardial fibrosis and preserved LVEF. The patient has returned to full-time work. Hindawi 2018-06-14 /pmc/articles/PMC6022326/ /pubmed/30013801 http://dx.doi.org/10.1155/2018/5698739 Text en Copyright © 2018 Abdalla Ibrahim et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Ibrahim, Abdalla Meagher, Eoghan Fraser, Alexander Kiernan, Thomas J. A Young Male with Severe Myocarditis and Skeletal Muscle Myositis |
title | A Young Male with Severe Myocarditis and Skeletal Muscle Myositis |
title_full | A Young Male with Severe Myocarditis and Skeletal Muscle Myositis |
title_fullStr | A Young Male with Severe Myocarditis and Skeletal Muscle Myositis |
title_full_unstemmed | A Young Male with Severe Myocarditis and Skeletal Muscle Myositis |
title_short | A Young Male with Severe Myocarditis and Skeletal Muscle Myositis |
title_sort | young male with severe myocarditis and skeletal muscle myositis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022326/ https://www.ncbi.nlm.nih.gov/pubmed/30013801 http://dx.doi.org/10.1155/2018/5698739 |
work_keys_str_mv | AT ibrahimabdalla ayoungmalewithseveremyocarditisandskeletalmusclemyositis AT meaghereoghan ayoungmalewithseveremyocarditisandskeletalmusclemyositis AT fraseralexander ayoungmalewithseveremyocarditisandskeletalmusclemyositis AT kiernanthomasj ayoungmalewithseveremyocarditisandskeletalmusclemyositis AT ibrahimabdalla youngmalewithseveremyocarditisandskeletalmusclemyositis AT meaghereoghan youngmalewithseveremyocarditisandskeletalmusclemyositis AT fraseralexander youngmalewithseveremyocarditisandskeletalmusclemyositis AT kiernanthomasj youngmalewithseveremyocarditisandskeletalmusclemyositis |