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A Young Male with Severe Myocarditis and Skeletal Muscle Myositis

A 34-year-old male presented with retrosternal chest pain, fatigue, shortness of breath, and a history of a previous episode of myocarditis four years prior. He had elevated troponin T, normal skeletal muscle enzymes, and negative inflammatory markers. Cardiac magnetic resonance imaging (MRI) confir...

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Autores principales: Ibrahim, Abdalla, Meagher, Eoghan, Fraser, Alexander, Kiernan, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022326/
https://www.ncbi.nlm.nih.gov/pubmed/30013801
http://dx.doi.org/10.1155/2018/5698739
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author Ibrahim, Abdalla
Meagher, Eoghan
Fraser, Alexander
Kiernan, Thomas J.
author_facet Ibrahim, Abdalla
Meagher, Eoghan
Fraser, Alexander
Kiernan, Thomas J.
author_sort Ibrahim, Abdalla
collection PubMed
description A 34-year-old male presented with retrosternal chest pain, fatigue, shortness of breath, and a history of a previous episode of myocarditis four years prior. He had elevated troponin T, normal skeletal muscle enzymes, and negative inflammatory markers. Cardiac magnetic resonance imaging (MRI) confirmed active myocarditis with extensive myocardial fibrosis and normal left ventricular ejection fraction (LVEF). His myocarditis symptoms resolved with steroids and anti-inflammatory treatment, but on closer questioning, he reported a vague history of long-standing calf discomfort associated with episodes of stiffness, fatigue, and flu-like symptoms. MRI of the lower legs consequently demonstrated active myositis in the calf muscles. Immunomodulatory therapy was commenced with good effect. The patient is undergoing regular follow-up in both cardiology and rheumatology outpatient departments. Repeated MRI of the legs showed significant interval improvement in his skeletal muscle myositis, and repeat cardiac MRI demonstrated the resolution of myocarditis along with persistent stable extensive myocardial fibrosis and preserved LVEF. The patient has returned to full-time work.
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spelling pubmed-60223262018-07-16 A Young Male with Severe Myocarditis and Skeletal Muscle Myositis Ibrahim, Abdalla Meagher, Eoghan Fraser, Alexander Kiernan, Thomas J. Case Rep Cardiol Case Report A 34-year-old male presented with retrosternal chest pain, fatigue, shortness of breath, and a history of a previous episode of myocarditis four years prior. He had elevated troponin T, normal skeletal muscle enzymes, and negative inflammatory markers. Cardiac magnetic resonance imaging (MRI) confirmed active myocarditis with extensive myocardial fibrosis and normal left ventricular ejection fraction (LVEF). His myocarditis symptoms resolved with steroids and anti-inflammatory treatment, but on closer questioning, he reported a vague history of long-standing calf discomfort associated with episodes of stiffness, fatigue, and flu-like symptoms. MRI of the lower legs consequently demonstrated active myositis in the calf muscles. Immunomodulatory therapy was commenced with good effect. The patient is undergoing regular follow-up in both cardiology and rheumatology outpatient departments. Repeated MRI of the legs showed significant interval improvement in his skeletal muscle myositis, and repeat cardiac MRI demonstrated the resolution of myocarditis along with persistent stable extensive myocardial fibrosis and preserved LVEF. The patient has returned to full-time work. Hindawi 2018-06-14 /pmc/articles/PMC6022326/ /pubmed/30013801 http://dx.doi.org/10.1155/2018/5698739 Text en Copyright © 2018 Abdalla Ibrahim et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ibrahim, Abdalla
Meagher, Eoghan
Fraser, Alexander
Kiernan, Thomas J.
A Young Male with Severe Myocarditis and Skeletal Muscle Myositis
title A Young Male with Severe Myocarditis and Skeletal Muscle Myositis
title_full A Young Male with Severe Myocarditis and Skeletal Muscle Myositis
title_fullStr A Young Male with Severe Myocarditis and Skeletal Muscle Myositis
title_full_unstemmed A Young Male with Severe Myocarditis and Skeletal Muscle Myositis
title_short A Young Male with Severe Myocarditis and Skeletal Muscle Myositis
title_sort young male with severe myocarditis and skeletal muscle myositis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022326/
https://www.ncbi.nlm.nih.gov/pubmed/30013801
http://dx.doi.org/10.1155/2018/5698739
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