Cargando…
ClC-2 knockdown prevents cerebrovascular remodeling via inhibition of the Wnt/β-catenin signaling pathway
BACKGROUND: Mishandling of intracellular chloride (Cl(−)) concentration ([Cl(−)](i)) in cerebrovascular smooth muscle cells is implicated in several pathological processes, including hyperplasia and remodeling. We investigated the effects of ClC-2-mediated Cl(−) efflux on the proliferation of human...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022329/ https://www.ncbi.nlm.nih.gov/pubmed/29988306 http://dx.doi.org/10.1186/s11658-018-0095-z |