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ClC-2 knockdown prevents cerebrovascular remodeling via inhibition of the Wnt/β-catenin signaling pathway
BACKGROUND: Mishandling of intracellular chloride (Cl(−)) concentration ([Cl(−)](i)) in cerebrovascular smooth muscle cells is implicated in several pathological processes, including hyperplasia and remodeling. We investigated the effects of ClC-2-mediated Cl(−) efflux on the proliferation of human...
Autores principales: | Lu, Jingjing, Xu, Feng, Zhang, Yingna, Lu, Hong, Zhang, Jiewen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022329/ https://www.ncbi.nlm.nih.gov/pubmed/29988306 http://dx.doi.org/10.1186/s11658-018-0095-z |
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