Second month sputum smear as a predictor of tuberculosis treatment outcomes in Brazil

OBJECTIVE: The value of sputum smear microscopy (SSM) after 2 months of treatment in the management of pulmonary tuberculosis is controversial. We analysed second month-SSM conversion as a predictor of treatment success in Brazil. RESULTS: Overall successful outcome rate was 89.4%. The predictive va...

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Detalles Bibliográficos
Autores principales: do Socorro Nantua Evangelista, Maria, Maia, Rosalia, Toledo, João Paulo, de Abreu, Ricardo Gadelha, Braga, José Uereles, Barreira, Draurio, Trajman, Anete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022340/
https://www.ncbi.nlm.nih.gov/pubmed/29954436
http://dx.doi.org/10.1186/s13104-018-3522-3
Descripción
Sumario:OBJECTIVE: The value of sputum smear microscopy (SSM) after 2 months of treatment in the management of pulmonary tuberculosis is controversial. We analysed second month-SSM conversion as a predictor of treatment success in Brazil. RESULTS: Overall successful outcome rate was 89.4%. The predictive value of second month-SSM conversion for successful outcomes was 85.2% 72,479/85,118), while the predictive value of non-conversion for unfavourable outcomes was 26.9% (2712/10,071). Unfavourable treatment outcomes were twice more likely among patients who did not convert (adjusted OR = 2.06; 1.97–2.16).

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