Second month sputum smear as a predictor of tuberculosis treatment outcomes in Brazil

OBJECTIVE: The value of sputum smear microscopy (SSM) after 2 months of treatment in the management of pulmonary tuberculosis is controversial. We analysed second month-SSM conversion as a predictor of treatment success in Brazil. RESULTS: Overall successful outcome rate was 89.4%. The predictive va...

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Autores principales: do Socorro Nantua Evangelista, Maria, Maia, Rosalia, Toledo, João Paulo, de Abreu, Ricardo Gadelha, Braga, José Uereles, Barreira, Draurio, Trajman, Anete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022340/
https://www.ncbi.nlm.nih.gov/pubmed/29954436
http://dx.doi.org/10.1186/s13104-018-3522-3
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author do Socorro Nantua Evangelista, Maria
Maia, Rosalia
Toledo, João Paulo
de Abreu, Ricardo Gadelha
Braga, José Uereles
Barreira, Draurio
Trajman, Anete
author_facet do Socorro Nantua Evangelista, Maria
Maia, Rosalia
Toledo, João Paulo
de Abreu, Ricardo Gadelha
Braga, José Uereles
Barreira, Draurio
Trajman, Anete
author_sort do Socorro Nantua Evangelista, Maria
collection PubMed
description OBJECTIVE: The value of sputum smear microscopy (SSM) after 2 months of treatment in the management of pulmonary tuberculosis is controversial. We analysed second month-SSM conversion as a predictor of treatment success in Brazil. RESULTS: Overall successful outcome rate was 89.4%. The predictive value of second month-SSM conversion for successful outcomes was 85.2% 72,479/85,118), while the predictive value of non-conversion for unfavourable outcomes was 26.9% (2712/10,071). Unfavourable treatment outcomes were twice more likely among patients who did not convert (adjusted OR = 2.06; 1.97–2.16).
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spelling pubmed-60223402018-07-09 Second month sputum smear as a predictor of tuberculosis treatment outcomes in Brazil do Socorro Nantua Evangelista, Maria Maia, Rosalia Toledo, João Paulo de Abreu, Ricardo Gadelha Braga, José Uereles Barreira, Draurio Trajman, Anete BMC Res Notes Research Note OBJECTIVE: The value of sputum smear microscopy (SSM) after 2 months of treatment in the management of pulmonary tuberculosis is controversial. We analysed second month-SSM conversion as a predictor of treatment success in Brazil. RESULTS: Overall successful outcome rate was 89.4%. The predictive value of second month-SSM conversion for successful outcomes was 85.2% 72,479/85,118), while the predictive value of non-conversion for unfavourable outcomes was 26.9% (2712/10,071). Unfavourable treatment outcomes were twice more likely among patients who did not convert (adjusted OR = 2.06; 1.97–2.16). BioMed Central 2018-06-28 /pmc/articles/PMC6022340/ /pubmed/29954436 http://dx.doi.org/10.1186/s13104-018-3522-3 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
do Socorro Nantua Evangelista, Maria
Maia, Rosalia
Toledo, João Paulo
de Abreu, Ricardo Gadelha
Braga, José Uereles
Barreira, Draurio
Trajman, Anete
Second month sputum smear as a predictor of tuberculosis treatment outcomes in Brazil
title Second month sputum smear as a predictor of tuberculosis treatment outcomes in Brazil
title_full Second month sputum smear as a predictor of tuberculosis treatment outcomes in Brazil
title_fullStr Second month sputum smear as a predictor of tuberculosis treatment outcomes in Brazil
title_full_unstemmed Second month sputum smear as a predictor of tuberculosis treatment outcomes in Brazil
title_short Second month sputum smear as a predictor of tuberculosis treatment outcomes in Brazil
title_sort second month sputum smear as a predictor of tuberculosis treatment outcomes in brazil
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022340/
https://www.ncbi.nlm.nih.gov/pubmed/29954436
http://dx.doi.org/10.1186/s13104-018-3522-3
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