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BaxΔ2 sensitizes colorectal cancer cells to proteasome inhibitor-induced cell death
Proteasome inhibitors, such as bortezomib and carfilzomib, are FDA approved for the treatment of hemopoietic cancers, but recent studies have shown their great potential for treatment of solid tumors. BaxΔ2, a unique proapoptotic Bax isoform, promotes non-mitochondrial cell death and sensitizes canc...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022363/ https://www.ncbi.nlm.nih.gov/pubmed/29291406 http://dx.doi.org/10.1016/j.bbrc.2017.12.156 |