Cargando…

Puerarin protects rat brain against ischemia/reperfusion injury by suppressing autophagy via the AMPK-mTOR-ULK1 signaling pathway

Puerarin suppresses autophagy to alleviate cerebral ischemia/reperfusion injury, and accumulating evidence indicates that the AMPK-mTOR signaling pathway regulates the activation of the autophagy pathway through the coordinated phosphorylation of ULK1. In this study, we investigated the mechanisms u...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jin-Feng, Mei, Zhi-Gang, Fu, Yang, Yang, Song-Bai, Zhang, Shi-Zhong, Huang, Wei-Feng, Xiong, Li, Zhou, Hua-Jun, Tao, Wei, Feng, Zhi-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022469/
https://www.ncbi.nlm.nih.gov/pubmed/29926825
http://dx.doi.org/10.4103/1673-5374.233441

Ejemplares similares