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Protein threading using residue co-variation and deep learning

MOTIVATION: Template-based modeling, including homology modeling and protein threading, is a popular method for protein 3D structure prediction. However, alignment generation and template selection for protein sequences without close templates remain very challenging. RESULTS: We present a new metho...

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Detalles Bibliográficos
Autores principales:	Zhu, Jianwei, Wang, Sheng, Bu, Dongbo, Xu, Jinbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Ismb 2018–Intelligent Systems for Molecular Biology Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022550/ https://www.ncbi.nlm.nih.gov/pubmed/29949980 http://dx.doi.org/10.1093/bioinformatics/bty278

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