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Quantifying the similarity of topological domains across normal and cancer human cell types
MOTIVATION: Three-dimensional chromosome structure has been increasingly shown to influence various levels of cellular and genomic functions. Through Hi-C data, which maps contact frequency on chromosomes, it has been found that structural elements termed topologically associating domains (TADs) are...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022623/ https://www.ncbi.nlm.nih.gov/pubmed/29949963 http://dx.doi.org/10.1093/bioinformatics/bty265 |