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mGPfusion: predicting protein stability changes with Gaussian process kernel learning and data fusion
MOTIVATION: Proteins are commonly used by biochemical industry for numerous processes. Refining these proteins’ properties via mutations causes stability effects as well. Accurate computational method to predict how mutations affect protein stability is necessary to facilitate efficient protein desi...
Autores principales: | Jokinen, Emmi, Heinonen, Markus, Lähdesmäki, Harri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022679/ https://www.ncbi.nlm.nih.gov/pubmed/29949987 http://dx.doi.org/10.1093/bioinformatics/bty238 |
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