Inhibiting tumor necrosis factor‐alpha at time of induced intervertebral disc injury limits long‐term pain and degeneration in a rat model

BACKGROUND: Painful intervertebral disc (IVD) degeneration has tremendous societal costs and few effective therapies. Intradiscal tumor necrosis factor‐alpha (TNFα) is commonly associated with low back pain, but the direct relationship remains unclear. PURPOSE: Treatment strategies for low back pain...

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Detalles Bibliográficos
Autores principales: Evashwick‐Rogler, Thomas W., Lai, Alon, Watanabe, Hironobu, Salandra, Jonathan M., Winkelstein, Beth A., Cho, Samuel K., Hecht, Andrew C., Iatridis, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022768/
https://www.ncbi.nlm.nih.gov/pubmed/29963655
http://dx.doi.org/10.1002/jsp2.1014

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