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Structural Transition and Antibody Binding of EBOV GP and ZIKV E Proteins from Pre-Fusion to Fusion-Initiation State
Membrane fusion proteins are responsible for viral entry into host cells—a crucial first step in viral infection. These proteins undergo large conformational changes from pre-fusion to fusion-initiation structures, and, despite differences in viral genomes and disease etiology, many fusion proteins...
Autores principales: | Lappala, Anna, Nishima, Wataru, Miner, Jacob, Fenimore, Paul, Fischer, Will, Hraber, Peter, Zhang, Ming, McMahon, Benjamin, Tung, Chang-Shung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022868/ https://www.ncbi.nlm.nih.gov/pubmed/29748487 http://dx.doi.org/10.3390/biom8020025 |
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