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Unraveling Nutritional Regulation of Tacrolimus Biosynthesis in Streptomyces tsukubaensis through omic Approaches

Streptomyces tsukubaensis stands out among actinomycetes by its ability to produce the immunosuppressant tacrolimus. Discovered about 30 years ago, this macrolide is widely used as immunosuppressant in current clinics. Other potential applications for the treatment of cancer and as neuroprotective a...

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Detalles Bibliográficos
Autores principales:	Ordóñez-Robles, María, Santos-Beneit, Fernando, Martín, Juan F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022917/ https://www.ncbi.nlm.nih.gov/pubmed/29724001 http://dx.doi.org/10.3390/antibiotics7020039

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