The Cellular Mechanisms that Ensure an Efficient Secretion in Streptomyces

Gram-positive soil bacteria included in the genus Streptomyces produce a large variety of secondary metabolites in addition to extracellular hydrolytic enzymes. From the industrial and commercial viewpoints, the S. lividans strain has generated greater interest as a host bacterium for the overproduc...

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Detalles Bibliográficos
Autores principales: Gullón, Sonia, Mellado, Rafael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022935/
https://www.ncbi.nlm.nih.gov/pubmed/29661993
http://dx.doi.org/10.3390/antibiotics7020033
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author Gullón, Sonia
Mellado, Rafael P.
author_facet Gullón, Sonia
Mellado, Rafael P.
author_sort Gullón, Sonia
collection PubMed
description Gram-positive soil bacteria included in the genus Streptomyces produce a large variety of secondary metabolites in addition to extracellular hydrolytic enzymes. From the industrial and commercial viewpoints, the S. lividans strain has generated greater interest as a host bacterium for the overproduction of homologous and heterologous hydrolytic enzymes as an industrial application, which has considerably increased scientific interest in the characterization of secretion routes in this bacterium. This review will focus on the secretion machinery in S. lividans.
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spelling pubmed-60229352018-07-02 The Cellular Mechanisms that Ensure an Efficient Secretion in Streptomyces Gullón, Sonia Mellado, Rafael P. Antibiotics (Basel) Review Gram-positive soil bacteria included in the genus Streptomyces produce a large variety of secondary metabolites in addition to extracellular hydrolytic enzymes. From the industrial and commercial viewpoints, the S. lividans strain has generated greater interest as a host bacterium for the overproduction of homologous and heterologous hydrolytic enzymes as an industrial application, which has considerably increased scientific interest in the characterization of secretion routes in this bacterium. This review will focus on the secretion machinery in S. lividans. MDPI 2018-04-14 /pmc/articles/PMC6022935/ /pubmed/29661993 http://dx.doi.org/10.3390/antibiotics7020033 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gullón, Sonia
Mellado, Rafael P.
The Cellular Mechanisms that Ensure an Efficient Secretion in Streptomyces
title The Cellular Mechanisms that Ensure an Efficient Secretion in Streptomyces
title_full The Cellular Mechanisms that Ensure an Efficient Secretion in Streptomyces
title_fullStr The Cellular Mechanisms that Ensure an Efficient Secretion in Streptomyces
title_full_unstemmed The Cellular Mechanisms that Ensure an Efficient Secretion in Streptomyces
title_short The Cellular Mechanisms that Ensure an Efficient Secretion in Streptomyces
title_sort cellular mechanisms that ensure an efficient secretion in streptomyces
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022935/
https://www.ncbi.nlm.nih.gov/pubmed/29661993
http://dx.doi.org/10.3390/antibiotics7020033
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