Cargando…
The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories
The limbic-reticular coupling theory suggests that the hippocampus and amygdala regulate such descending limbic structures as the mammillary bodies, septum, hypothalamus and epithalamus to regulate the ascending noradrenergic, serotonergic, dopaminergic and cholinergic systems, performing declarativ...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação de Neurologia Cognitiva e do Comportamento
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022992/ https://www.ncbi.nlm.nih.gov/pubmed/29988336 http://dx.doi.org/10.1590/1980-57642018dn12-020002 |
_version_ | 1783335770169278464 |
---|---|
author | Cai, Zi-Jian |
author_facet | Cai, Zi-Jian |
author_sort | Cai, Zi-Jian |
collection | PubMed |
description | The limbic-reticular coupling theory suggests that the hippocampus and amygdala regulate such descending limbic structures as the mammillary bodies, septum, hypothalamus and epithalamus to regulate the ascending noradrenergic, serotonergic, dopaminergic and cholinergic systems, performing declarative memory consolidation and recall. Recent studies have revealed that, less sensitive to familiarity, the hippocampus functions via the fornix, mammillary bodies and hypothalamus for memory recall. Lesions to the thalamic nuclei were complicated with damage to adjacent fornix, stria medullaris and habenula, simultaneously destroying two kinds of structures respectively for familiarity and recall. Furthermore, the orbitofrontal cortex was shown to be clinically irrelevant for memory recall. Electrophysiologically, the hippocampus regulates the raphe nuclei in complex ways, and the hippocampal theta wave activates the dopaminergic cells in ventral tegmental area and cholinergic neurons in basal forebrain, while cholinergic-modulated theta-gamma coupling mediates cortical recall. These concurrent advances support the limbic-reticular coupling theory for elucidation of memory recall. |
format | Online Article Text |
id | pubmed-6022992 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Associação de Neurologia Cognitiva e do Comportamento |
record_format | MEDLINE/PubMed |
spelling | pubmed-60229922018-07-09 The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories Cai, Zi-Jian Dement Neuropsychol Views & Reviews The limbic-reticular coupling theory suggests that the hippocampus and amygdala regulate such descending limbic structures as the mammillary bodies, septum, hypothalamus and epithalamus to regulate the ascending noradrenergic, serotonergic, dopaminergic and cholinergic systems, performing declarative memory consolidation and recall. Recent studies have revealed that, less sensitive to familiarity, the hippocampus functions via the fornix, mammillary bodies and hypothalamus for memory recall. Lesions to the thalamic nuclei were complicated with damage to adjacent fornix, stria medullaris and habenula, simultaneously destroying two kinds of structures respectively for familiarity and recall. Furthermore, the orbitofrontal cortex was shown to be clinically irrelevant for memory recall. Electrophysiologically, the hippocampus regulates the raphe nuclei in complex ways, and the hippocampal theta wave activates the dopaminergic cells in ventral tegmental area and cholinergic neurons in basal forebrain, while cholinergic-modulated theta-gamma coupling mediates cortical recall. These concurrent advances support the limbic-reticular coupling theory for elucidation of memory recall. Associação de Neurologia Cognitiva e do Comportamento 2018 /pmc/articles/PMC6022992/ /pubmed/29988336 http://dx.doi.org/10.1590/1980-57642018dn12-020002 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Views & Reviews Cai, Zi-Jian The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories |
title | The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories |
title_full | The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories |
title_fullStr | The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories |
title_full_unstemmed | The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories |
title_short | The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories |
title_sort | limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories |
topic | Views & Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022992/ https://www.ncbi.nlm.nih.gov/pubmed/29988336 http://dx.doi.org/10.1590/1980-57642018dn12-020002 |
work_keys_str_mv | AT caizijian thelimbicreticularcouplingtheoryofmemoryprocessinginthebrainanditsgreatercompatibilityoverothertheories AT caizijian limbicreticularcouplingtheoryofmemoryprocessinginthebrainanditsgreatercompatibilityoverothertheories |