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The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories

The limbic-reticular coupling theory suggests that the hippocampus and amygdala regulate such descending limbic structures as the mammillary bodies, septum, hypothalamus and epithalamus to regulate the ascending noradrenergic, serotonergic, dopaminergic and cholinergic systems, performing declarativ...

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Autor principal: Cai, Zi-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Neurologia Cognitiva e do Comportamento 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022992/
https://www.ncbi.nlm.nih.gov/pubmed/29988336
http://dx.doi.org/10.1590/1980-57642018dn12-020002
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author Cai, Zi-Jian
author_facet Cai, Zi-Jian
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description The limbic-reticular coupling theory suggests that the hippocampus and amygdala regulate such descending limbic structures as the mammillary bodies, septum, hypothalamus and epithalamus to regulate the ascending noradrenergic, serotonergic, dopaminergic and cholinergic systems, performing declarative memory consolidation and recall. Recent studies have revealed that, less sensitive to familiarity, the hippocampus functions via the fornix, mammillary bodies and hypothalamus for memory recall. Lesions to the thalamic nuclei were complicated with damage to adjacent fornix, stria medullaris and habenula, simultaneously destroying two kinds of structures respectively for familiarity and recall. Furthermore, the orbitofrontal cortex was shown to be clinically irrelevant for memory recall. Electrophysiologically, the hippocampus regulates the raphe nuclei in complex ways, and the hippocampal theta wave activates the dopaminergic cells in ventral tegmental area and cholinergic neurons in basal forebrain, while cholinergic-modulated theta-gamma coupling mediates cortical recall. These concurrent advances support the limbic-reticular coupling theory for elucidation of memory recall.
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spelling pubmed-60229922018-07-09 The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories Cai, Zi-Jian Dement Neuropsychol Views & Reviews The limbic-reticular coupling theory suggests that the hippocampus and amygdala regulate such descending limbic structures as the mammillary bodies, septum, hypothalamus and epithalamus to regulate the ascending noradrenergic, serotonergic, dopaminergic and cholinergic systems, performing declarative memory consolidation and recall. Recent studies have revealed that, less sensitive to familiarity, the hippocampus functions via the fornix, mammillary bodies and hypothalamus for memory recall. Lesions to the thalamic nuclei were complicated with damage to adjacent fornix, stria medullaris and habenula, simultaneously destroying two kinds of structures respectively for familiarity and recall. Furthermore, the orbitofrontal cortex was shown to be clinically irrelevant for memory recall. Electrophysiologically, the hippocampus regulates the raphe nuclei in complex ways, and the hippocampal theta wave activates the dopaminergic cells in ventral tegmental area and cholinergic neurons in basal forebrain, while cholinergic-modulated theta-gamma coupling mediates cortical recall. These concurrent advances support the limbic-reticular coupling theory for elucidation of memory recall. Associação de Neurologia Cognitiva e do Comportamento 2018 /pmc/articles/PMC6022992/ /pubmed/29988336 http://dx.doi.org/10.1590/1980-57642018dn12-020002 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Views & Reviews
Cai, Zi-Jian
The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories
title The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories
title_full The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories
title_fullStr The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories
title_full_unstemmed The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories
title_short The limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories
title_sort limbic-reticular coupling theory of memory processing in the brain and its greater compatibility over other theories
topic Views & Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022992/
https://www.ncbi.nlm.nih.gov/pubmed/29988336
http://dx.doi.org/10.1590/1980-57642018dn12-020002
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