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The Effect of Overexpressed DdRabS on Development, Cell Death, Vesicular Trafficking, and the Secretion of Lysosomal Glycosidase Enzymes

Rab GTPases are essential regulators of many cellular processes and play an important role in downstream signaling vital to proper cell function. We sought to elucidate the role of novel D. discoideum GTPase RabS. Cell lines over-expressing DdRabS and expressing DdRabS N137I (dominant negative (DN))...

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Detalles Bibliográficos
Autores principales: Yarbrough, Azure, Maringer, Katherine, Saheb, Entsar J., Jawed, Sanaa, Bush, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023087/
https://www.ncbi.nlm.nih.gov/pubmed/29843387
http://dx.doi.org/10.3390/biology7020033