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The Effect of Overexpressed DdRabS on Development, Cell Death, Vesicular Trafficking, and the Secretion of Lysosomal Glycosidase Enzymes
Rab GTPases are essential regulators of many cellular processes and play an important role in downstream signaling vital to proper cell function. We sought to elucidate the role of novel D. discoideum GTPase RabS. Cell lines over-expressing DdRabS and expressing DdRabS N137I (dominant negative (DN))...
Autores principales: | Yarbrough, Azure, Maringer, Katherine, Saheb, Entsar J., Jawed, Sanaa, Bush, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023087/ https://www.ncbi.nlm.nih.gov/pubmed/29843387 http://dx.doi.org/10.3390/biology7020033 |
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