Cargando…

Loxl2 is dispensable for dermal development, homeostasis and tumour stroma formation

Lysyl oxidase-like 2 (LOXL2) is a copper-dependent monoamine oxidase that contributes to the remodelling of the extracellular matrix (ECM) by cross linkage of collagen and elastin fibres and has emerged as a potential therapeutic target in cancer and fibrosis. In the skin, LOXL2 is essential for epi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kober, Katharina Isabelle, Cano, Amparo, Géraud, Cyrill, Sipilä, Kalle, Mobasseri, Seyedeh Atefeh, Philippeos, Christina, Pisco, Angela Oliveira, Stannard, Andrew, Martin, Alberto, Salvador, Fernando, Santos, Vanesa, Boutros, Michael, Rognoni, Emanuel, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023175/
https://www.ncbi.nlm.nih.gov/pubmed/29953488
http://dx.doi.org/10.1371/journal.pone.0199679