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Loxl2 is dispensable for dermal development, homeostasis and tumour stroma formation
Lysyl oxidase-like 2 (LOXL2) is a copper-dependent monoamine oxidase that contributes to the remodelling of the extracellular matrix (ECM) by cross linkage of collagen and elastin fibres and has emerged as a potential therapeutic target in cancer and fibrosis. In the skin, LOXL2 is essential for epi...
Autores principales: | Kober, Katharina Isabelle, Cano, Amparo, Géraud, Cyrill, Sipilä, Kalle, Mobasseri, Seyedeh Atefeh, Philippeos, Christina, Pisco, Angela Oliveira, Stannard, Andrew, Martin, Alberto, Salvador, Fernando, Santos, Vanesa, Boutros, Michael, Rognoni, Emanuel, Watt, Fiona M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023175/ https://www.ncbi.nlm.nih.gov/pubmed/29953488 http://dx.doi.org/10.1371/journal.pone.0199679 |
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