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High content, high-throughput screening for small molecule inducers of NF-κB translocation
NF-κB is an important mediator of immune activity and its activation is essential in mounting immune response to pathogens. Here, we describe the optimization and implementation of a high-throughput screening platform that utilizes high content imaging and analysis to monitor NF-κB nuclear transloca...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023200/ https://www.ncbi.nlm.nih.gov/pubmed/29953522 http://dx.doi.org/10.1371/journal.pone.0199966 |