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Reversing allosteric communication: From detecting allosteric sites to inducing and tuning targeted allosteric response
The omnipresence of allosteric regulation together with the fundamental role of structural dynamics in this phenomenon have initiated a great interest to the detection of regulatory exosites and design of corresponding effectors. However, despite a general consensus on the key role of dynamics most...
Autores principales: | Tee, Wei-Ven, Guarnera, Enrico, Berezovsky, Igor N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023240/ https://www.ncbi.nlm.nih.gov/pubmed/29912863 http://dx.doi.org/10.1371/journal.pcbi.1006228 |
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