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Unique patterns of trimethylation of histone H3 lysine 4 are prone to changes during aging in Caenorhabditis elegans somatic cells

Tri-methylation on histone H3 lysine 4 (H3K4me3) is associated with active gene expression but its regulatory role in transcriptional activation is unclear. Here we used Caenorhabditis elegans to investigate the connection between H3K4me3 and gene expression regulation during aging. We uncovered aro...

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Detalles Bibliográficos
Autores principales:	Pu, Mintie, Wang, Minghui, Wang, Wenke, Velayudhan, Satheeja Santhi, Lee, Siu Sylvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023244/ https://www.ncbi.nlm.nih.gov/pubmed/29912876 http://dx.doi.org/10.1371/journal.pgen.1007466

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