Cargando…

What Is the Heart? Anatomy, Function, Pathophysiology, and Misconceptions

Cardiac dynamics are traditionally linked to a left ventricle, right ventricle, and septum morphology, a topography that differs from the heart’s five-century-old anatomic description of containing a helix and circumferential wrap architectural configuration. Torrent Guasp’s helical ventricular myoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Buckberg, Gerald D., Nanda, Navin C., Nguyen, Christopher, Kocica, Mladen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023278/
https://www.ncbi.nlm.nih.gov/pubmed/29867011
http://dx.doi.org/10.3390/jcdd5020033
_version_ 1783335835817476096
author Buckberg, Gerald D.
Nanda, Navin C.
Nguyen, Christopher
Kocica, Mladen J.
author_facet Buckberg, Gerald D.
Nanda, Navin C.
Nguyen, Christopher
Kocica, Mladen J.
author_sort Buckberg, Gerald D.
collection PubMed
description Cardiac dynamics are traditionally linked to a left ventricle, right ventricle, and septum morphology, a topography that differs from the heart’s five-century-old anatomic description of containing a helix and circumferential wrap architectural configuration. Torrent Guasp’s helical ventricular myocardial band (HVMB) defines this anatomy and its structure, and explains why the heart’s six dynamic actions of narrowing, shortening, lengthening, widening, twisting, and uncoiling happen. The described structural findings will raise questions about deductions guiding “accepted cardiac mechanics”, and their functional aspects will challenge and overturn them. These suppositions include the LV, RV, and septum description, timing of mitral valve opening, isovolumic relaxation period, reasons for torsion/twisting, untwisting, reasons for longitudinal and circumferential strain, echocardiographic sub segmentation, resynchronization, RV function dynamics, diastolic dysfunction’s cause, and unrecognized septum impairment. Torrent Guasp’s revolutionary contributions may alter future understanding of the diagnosis and treatment of cardiac disease.
format Online
Article
Text
id pubmed-6023278
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-60232782018-07-05 What Is the Heart? Anatomy, Function, Pathophysiology, and Misconceptions Buckberg, Gerald D. Nanda, Navin C. Nguyen, Christopher Kocica, Mladen J. J Cardiovasc Dev Dis Review Cardiac dynamics are traditionally linked to a left ventricle, right ventricle, and septum morphology, a topography that differs from the heart’s five-century-old anatomic description of containing a helix and circumferential wrap architectural configuration. Torrent Guasp’s helical ventricular myocardial band (HVMB) defines this anatomy and its structure, and explains why the heart’s six dynamic actions of narrowing, shortening, lengthening, widening, twisting, and uncoiling happen. The described structural findings will raise questions about deductions guiding “accepted cardiac mechanics”, and their functional aspects will challenge and overturn them. These suppositions include the LV, RV, and septum description, timing of mitral valve opening, isovolumic relaxation period, reasons for torsion/twisting, untwisting, reasons for longitudinal and circumferential strain, echocardiographic sub segmentation, resynchronization, RV function dynamics, diastolic dysfunction’s cause, and unrecognized septum impairment. Torrent Guasp’s revolutionary contributions may alter future understanding of the diagnosis and treatment of cardiac disease. MDPI 2018-06-04 /pmc/articles/PMC6023278/ /pubmed/29867011 http://dx.doi.org/10.3390/jcdd5020033 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Buckberg, Gerald D.
Nanda, Navin C.
Nguyen, Christopher
Kocica, Mladen J.
What Is the Heart? Anatomy, Function, Pathophysiology, and Misconceptions
title What Is the Heart? Anatomy, Function, Pathophysiology, and Misconceptions
title_full What Is the Heart? Anatomy, Function, Pathophysiology, and Misconceptions
title_fullStr What Is the Heart? Anatomy, Function, Pathophysiology, and Misconceptions
title_full_unstemmed What Is the Heart? Anatomy, Function, Pathophysiology, and Misconceptions
title_short What Is the Heart? Anatomy, Function, Pathophysiology, and Misconceptions
title_sort what is the heart? anatomy, function, pathophysiology, and misconceptions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023278/
https://www.ncbi.nlm.nih.gov/pubmed/29867011
http://dx.doi.org/10.3390/jcdd5020033
work_keys_str_mv AT buckberggeraldd whatistheheartanatomyfunctionpathophysiologyandmisconceptions
AT nandanavinc whatistheheartanatomyfunctionpathophysiologyandmisconceptions
AT nguyenchristopher whatistheheartanatomyfunctionpathophysiologyandmisconceptions
AT kocicamladenj whatistheheartanatomyfunctionpathophysiologyandmisconceptions