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Developments in Point-of-Care Diagnostic Technology for Cancer Detection

Cancer is the cause of death for one in seven individuals worldwide. It is widely acknowledged that screening and early diagnosis are of vital importance for improving the likelihood of recovery. However, given the costly, time-consuming, and invasive nature of the many methods currently in use, pat...

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Autores principales: Hayes, Bryony, Murphy, Caroline, Crawley, Aoife, O’Kennedy, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023377/
https://www.ncbi.nlm.nih.gov/pubmed/29865250
http://dx.doi.org/10.3390/diagnostics8020039
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author Hayes, Bryony
Murphy, Caroline
Crawley, Aoife
O’Kennedy, Richard
author_facet Hayes, Bryony
Murphy, Caroline
Crawley, Aoife
O’Kennedy, Richard
author_sort Hayes, Bryony
collection PubMed
description Cancer is the cause of death for one in seven individuals worldwide. It is widely acknowledged that screening and early diagnosis are of vital importance for improving the likelihood of recovery. However, given the costly, time-consuming, and invasive nature of the many methods currently in use, patients often do not take advantage of the services available to them. Consequently, many researchers are exploring the possibility of developing fast, reliable, and non-invasive diagnostic tools that can be used directly or by local physicians at the point-of-care. Herein, we look at the use of established biomarkers in cancer therapy and investigate emerging biomarkers exhibiting future potential. The incorporation of these biomarkers into point-of-care devices could potentially reduce the strain currently experienced by screening programs in hospitals and healthcare systems. Results derived from point-of-care tests should be accurate, sensitive, and generated rapidly to assist in the selection of the best course of treatment for optimal patient care. Essentially, point-of-care diagnostics should enhance the well-being of patients and lead to a reduction in cancer-related deaths.
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spelling pubmed-60233772018-07-13 Developments in Point-of-Care Diagnostic Technology for Cancer Detection Hayes, Bryony Murphy, Caroline Crawley, Aoife O’Kennedy, Richard Diagnostics (Basel) Review Cancer is the cause of death for one in seven individuals worldwide. It is widely acknowledged that screening and early diagnosis are of vital importance for improving the likelihood of recovery. However, given the costly, time-consuming, and invasive nature of the many methods currently in use, patients often do not take advantage of the services available to them. Consequently, many researchers are exploring the possibility of developing fast, reliable, and non-invasive diagnostic tools that can be used directly or by local physicians at the point-of-care. Herein, we look at the use of established biomarkers in cancer therapy and investigate emerging biomarkers exhibiting future potential. The incorporation of these biomarkers into point-of-care devices could potentially reduce the strain currently experienced by screening programs in hospitals and healthcare systems. Results derived from point-of-care tests should be accurate, sensitive, and generated rapidly to assist in the selection of the best course of treatment for optimal patient care. Essentially, point-of-care diagnostics should enhance the well-being of patients and lead to a reduction in cancer-related deaths. MDPI 2018-06-02 /pmc/articles/PMC6023377/ /pubmed/29865250 http://dx.doi.org/10.3390/diagnostics8020039 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hayes, Bryony
Murphy, Caroline
Crawley, Aoife
O’Kennedy, Richard
Developments in Point-of-Care Diagnostic Technology for Cancer Detection
title Developments in Point-of-Care Diagnostic Technology for Cancer Detection
title_full Developments in Point-of-Care Diagnostic Technology for Cancer Detection
title_fullStr Developments in Point-of-Care Diagnostic Technology for Cancer Detection
title_full_unstemmed Developments in Point-of-Care Diagnostic Technology for Cancer Detection
title_short Developments in Point-of-Care Diagnostic Technology for Cancer Detection
title_sort developments in point-of-care diagnostic technology for cancer detection
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023377/
https://www.ncbi.nlm.nih.gov/pubmed/29865250
http://dx.doi.org/10.3390/diagnostics8020039
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