Cell-type-specific brain methylomes profiled via ultralow-input microfluidics

Methylomic analyses typically require substantial amounts of DNA, thus hindering studies involving scarce samples. Here, we show that microfluidic diffusion-based reduced representative bisulfite sequencing (MID-RRBS) permits high-quality methylomic profiling with nanogram-to-single-cell quantities...

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Detalles Bibliográficos
Autores principales: Ma, Sai, de la Fuente Revenga, Mario, Sun, Zhixiong, Sun, Chen, Murphy, Travis W., Xie, Hehuang, González-Maeso, Javier, Lu, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023403/
https://www.ncbi.nlm.nih.gov/pubmed/29963329

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