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Microfluidic Devices for Drug Assays
In this review, we give an overview of the current state of microfluidic-based high-throughput drug assays. In this highly interdisciplinary research field, various approaches have been applied to high-throughput drug screening, including microtiter plate, droplets microfluidics as well as continuou...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023517/ https://www.ncbi.nlm.nih.gov/pubmed/29925804 http://dx.doi.org/10.3390/ht7020018 |
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author | Regnault, Clément Dheeman, Dharmendra S. Hochstetter, Axel |
author_facet | Regnault, Clément Dheeman, Dharmendra S. Hochstetter, Axel |
author_sort | Regnault, Clément |
collection | PubMed |
description | In this review, we give an overview of the current state of microfluidic-based high-throughput drug assays. In this highly interdisciplinary research field, various approaches have been applied to high-throughput drug screening, including microtiter plate, droplets microfluidics as well as continuous flow, diffusion and concentration gradients-based microfluidic drug assays. Therefore, we reviewed over 100 recent publications in the field and sorted them according to their microfluidic approach. As a result, we are showcasing, comparing and discussing broadly applied approaches as well as singular promising ones that might contribute to shaping the future of this field. |
format | Online Article Text |
id | pubmed-6023517 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-60235172018-07-03 Microfluidic Devices for Drug Assays Regnault, Clément Dheeman, Dharmendra S. Hochstetter, Axel High Throughput Review In this review, we give an overview of the current state of microfluidic-based high-throughput drug assays. In this highly interdisciplinary research field, various approaches have been applied to high-throughput drug screening, including microtiter plate, droplets microfluidics as well as continuous flow, diffusion and concentration gradients-based microfluidic drug assays. Therefore, we reviewed over 100 recent publications in the field and sorted them according to their microfluidic approach. As a result, we are showcasing, comparing and discussing broadly applied approaches as well as singular promising ones that might contribute to shaping the future of this field. MDPI 2018-06-20 /pmc/articles/PMC6023517/ /pubmed/29925804 http://dx.doi.org/10.3390/ht7020018 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Regnault, Clément Dheeman, Dharmendra S. Hochstetter, Axel Microfluidic Devices for Drug Assays |
title | Microfluidic Devices for Drug Assays |
title_full | Microfluidic Devices for Drug Assays |
title_fullStr | Microfluidic Devices for Drug Assays |
title_full_unstemmed | Microfluidic Devices for Drug Assays |
title_short | Microfluidic Devices for Drug Assays |
title_sort | microfluidic devices for drug assays |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023517/ https://www.ncbi.nlm.nih.gov/pubmed/29925804 http://dx.doi.org/10.3390/ht7020018 |
work_keys_str_mv | AT regnaultclement microfluidicdevicesfordrugassays AT dheemandharmendras microfluidicdevicesfordrugassays AT hochstetteraxel microfluidicdevicesfordrugassays |