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Pancreatic Cystic Lesions: Pathogenesis and Malignant Potential

Pancreatic cancer remains one of the most lethal cancers despite extensive research. Further understanding of precursor lesions may enhance the ability to treat and prevent pancreatic cancer. Pancreatic cystic lesions (PCLs) with malignant potential include: mucinous PCLs (intraductal papillary muci...

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Detalles Bibliográficos
Autores principales: Pusateri, Antoinette J., Krishna, Somashekar G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023528/
https://www.ncbi.nlm.nih.gov/pubmed/29899320
http://dx.doi.org/10.3390/diseases6020050
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author Pusateri, Antoinette J.
Krishna, Somashekar G.
author_facet Pusateri, Antoinette J.
Krishna, Somashekar G.
author_sort Pusateri, Antoinette J.
collection PubMed
description Pancreatic cancer remains one of the most lethal cancers despite extensive research. Further understanding of precursor lesions may enhance the ability to treat and prevent pancreatic cancer. Pancreatic cystic lesions (PCLs) with malignant potential include: mucinous PCLs (intraductal papillary mucinous neoplasms and mucinous cystic neoplasm), solid pseudopapillary tumors and cystic neuroendocrine tumors. This review summarizes the latest literature describing what is known about the pathogenesis and malignant potential of these PCLs, including unique epidemiological, radiological, histological, genetic and molecular characteristics.
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spelling pubmed-60235282018-07-03 Pancreatic Cystic Lesions: Pathogenesis and Malignant Potential Pusateri, Antoinette J. Krishna, Somashekar G. Diseases Review Pancreatic cancer remains one of the most lethal cancers despite extensive research. Further understanding of precursor lesions may enhance the ability to treat and prevent pancreatic cancer. Pancreatic cystic lesions (PCLs) with malignant potential include: mucinous PCLs (intraductal papillary mucinous neoplasms and mucinous cystic neoplasm), solid pseudopapillary tumors and cystic neuroendocrine tumors. This review summarizes the latest literature describing what is known about the pathogenesis and malignant potential of these PCLs, including unique epidemiological, radiological, histological, genetic and molecular characteristics. MDPI 2018-06-13 /pmc/articles/PMC6023528/ /pubmed/29899320 http://dx.doi.org/10.3390/diseases6020050 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Pusateri, Antoinette J.
Krishna, Somashekar G.
Pancreatic Cystic Lesions: Pathogenesis and Malignant Potential
title Pancreatic Cystic Lesions: Pathogenesis and Malignant Potential
title_full Pancreatic Cystic Lesions: Pathogenesis and Malignant Potential
title_fullStr Pancreatic Cystic Lesions: Pathogenesis and Malignant Potential
title_full_unstemmed Pancreatic Cystic Lesions: Pathogenesis and Malignant Potential
title_short Pancreatic Cystic Lesions: Pathogenesis and Malignant Potential
title_sort pancreatic cystic lesions: pathogenesis and malignant potential
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023528/
https://www.ncbi.nlm.nih.gov/pubmed/29899320
http://dx.doi.org/10.3390/diseases6020050
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