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Pheochromocytoma crisis presenting with hypotension, hemoptysis, and abnormal liver function: A case report

RATIONALE: Pheochromocytomas are rare catecholamine-secreting tumors arising from adrenomedullary chromaffin cells, usually causing hypertension, palpitation and headache. However, pheochromocytoma crisis, on the contrary, might present with hypotension, multiple organ dysfunction or even mimicking...

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Autores principales: Wu, Renhua, Tong, Nanwei, Chen, Xinlei, Xu, Shishi, Zhang, Fang, Tang, Lizhi, Zhang, Yuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023654/
https://www.ncbi.nlm.nih.gov/pubmed/29923996
http://dx.doi.org/10.1097/MD.0000000000011054
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author Wu, Renhua
Tong, Nanwei
Chen, Xinlei
Xu, Shishi
Zhang, Fang
Tang, Lizhi
Zhang, Yuwei
author_facet Wu, Renhua
Tong, Nanwei
Chen, Xinlei
Xu, Shishi
Zhang, Fang
Tang, Lizhi
Zhang, Yuwei
author_sort Wu, Renhua
collection PubMed
description RATIONALE: Pheochromocytomas are rare catecholamine-secreting tumors arising from adrenomedullary chromaffin cells, usually causing hypertension, palpitation and headache. However, pheochromocytoma crisis, on the contrary, might present with hypotension, multiple organ dysfunction or even mimicking other diseases, leaving physician with diagnostic difficulties. In this study, we present a case featured hypotension, shock and multiple organ dysfunction syndrome on admission, which nearly lead us to miss the diagnosis of pheochromocytoma. PATIENT CONCERNS: A 14-year-old female student presented with cough, hemoptysis and dyspnea for one week was reported. DIAGNOSES: The laboratory test showed significantly increase in plasma norepinephrine and 24-hour urine norepinephrine, the enhanced CT of bilateral adrenal gland showed two round-like masses (left: 4 × 5 × 3 cm; right: 6 × 4 × 3 cm) with soft tissue density in each adrenal gland. The post-surgical pathology confirmed the diagnosis of pheochromocytoma. INTERVENTIONS: The resection of bilateral adrenal tumors was conducted after the preoperative medical treatment of phenoxybenzamine for two weeks. OUTCOMES: The patient underwent follow-up for a year and a half and showed no signs of recurrence. LESSONS: The diagnosis and treatment process of the patient in this study indicates us that when we meet a patient with hypotension and multiple organ dysfunctions in a relatively short time, the suspicion of pheochromocytoma should not be missed.
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spelling pubmed-60236542018-07-03 Pheochromocytoma crisis presenting with hypotension, hemoptysis, and abnormal liver function: A case report Wu, Renhua Tong, Nanwei Chen, Xinlei Xu, Shishi Zhang, Fang Tang, Lizhi Zhang, Yuwei Medicine (Baltimore) Research Article RATIONALE: Pheochromocytomas are rare catecholamine-secreting tumors arising from adrenomedullary chromaffin cells, usually causing hypertension, palpitation and headache. However, pheochromocytoma crisis, on the contrary, might present with hypotension, multiple organ dysfunction or even mimicking other diseases, leaving physician with diagnostic difficulties. In this study, we present a case featured hypotension, shock and multiple organ dysfunction syndrome on admission, which nearly lead us to miss the diagnosis of pheochromocytoma. PATIENT CONCERNS: A 14-year-old female student presented with cough, hemoptysis and dyspnea for one week was reported. DIAGNOSES: The laboratory test showed significantly increase in plasma norepinephrine and 24-hour urine norepinephrine, the enhanced CT of bilateral adrenal gland showed two round-like masses (left: 4 × 5 × 3 cm; right: 6 × 4 × 3 cm) with soft tissue density in each adrenal gland. The post-surgical pathology confirmed the diagnosis of pheochromocytoma. INTERVENTIONS: The resection of bilateral adrenal tumors was conducted after the preoperative medical treatment of phenoxybenzamine for two weeks. OUTCOMES: The patient underwent follow-up for a year and a half and showed no signs of recurrence. LESSONS: The diagnosis and treatment process of the patient in this study indicates us that when we meet a patient with hypotension and multiple organ dysfunctions in a relatively short time, the suspicion of pheochromocytoma should not be missed. Wolters Kluwer Health 2018-06-22 /pmc/articles/PMC6023654/ /pubmed/29923996 http://dx.doi.org/10.1097/MD.0000000000011054 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle Research Article
Wu, Renhua
Tong, Nanwei
Chen, Xinlei
Xu, Shishi
Zhang, Fang
Tang, Lizhi
Zhang, Yuwei
Pheochromocytoma crisis presenting with hypotension, hemoptysis, and abnormal liver function: A case report
title Pheochromocytoma crisis presenting with hypotension, hemoptysis, and abnormal liver function: A case report
title_full Pheochromocytoma crisis presenting with hypotension, hemoptysis, and abnormal liver function: A case report
title_fullStr Pheochromocytoma crisis presenting with hypotension, hemoptysis, and abnormal liver function: A case report
title_full_unstemmed Pheochromocytoma crisis presenting with hypotension, hemoptysis, and abnormal liver function: A case report
title_short Pheochromocytoma crisis presenting with hypotension, hemoptysis, and abnormal liver function: A case report
title_sort pheochromocytoma crisis presenting with hypotension, hemoptysis, and abnormal liver function: a case report
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023654/
https://www.ncbi.nlm.nih.gov/pubmed/29923996
http://dx.doi.org/10.1097/MD.0000000000011054
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