Useful pharmacodynamic endpoints in children: selection, measurement, and next steps

Pharmacodynamic (PD) endpoints are essential for establishing the benefit-to-risk ratio for therapeutic interventions in children and neonates. This article discusses the selection of an appropriate measure of response, the PD endpoint, which is a critical methodological step in designing pediatric...

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Detalles Bibliográficos
Autores principales: Kelly, Lauren E, Sinha, Yashwant, Barker, Charlotte I S, Standing, Joseph F, Offringa, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023695/
https://www.ncbi.nlm.nih.gov/pubmed/29667952
http://dx.doi.org/10.1038/pr.2018.38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023695/
https://www.ncbi.nlm.nih.gov/pubmed/29667952
http://dx.doi.org/10.1038/pr.2018.38

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