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Spherical Nucleic Acid Architecture Can Improve the Efficacy of Polycation-Mediated siRNA Delivery

Clinical translation of small interfering RNA (siRNA) nanocarriers is hindered by limited knowledge regarding the parameters that regulate interactions between nanocarriers and biological systems. To address this, we investigated the influence of polycation-based nanocarrier architecture on intracel...

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Detalles Bibliográficos
Autores principales: Melamed, Jilian R., Kreuzberger, Nicole L., Goyal, Ritu, Day, Emily S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023847/
https://www.ncbi.nlm.nih.gov/pubmed/30195760
http://dx.doi.org/10.1016/j.omtn.2018.05.008

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