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Glutamate as a potential “survival factor” in an in vitro model of neuronal hypoxia/reoxygenation injury: leading role of the Na(+)/Ca(2+) exchanger

In brain ischemia, reduction in oxygen and substrates affects mitochondrial respiratory chain and aerobic metabolism, culminating in ATP production impairment, ionic imbalance, and cell death. The restoration of blood flow and reoxygenation are frequently associated with exacerbation of tissue injur...

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Detalles Bibliográficos
Autores principales:	Piccirillo, Silvia, Castaldo, Pasqualina, Macrì, Maria Loredana, Amoroso, Salvatore, Magi, Simona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023866/ https://www.ncbi.nlm.nih.gov/pubmed/29955038 http://dx.doi.org/10.1038/s41419-018-0784-6

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