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Epidermal-specific deletion of TC-PTP promotes UVB-induced epidermal cell survival through the regulation of Flk-1/JNK signaling

UVB exposure can contribute to the development of skin cancer by modulating protein tyrosine kinase (PTK) signaling. It has been suggested that UVB radiation increases the ligand-dependent activation of PTKs and induces PTP inactivation. Our recent studies have shown that T-cell protein tyrosine pho...

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Detalles Bibliográficos
Autores principales: Baek, Minwoo, Kim, Mihwa, Lim, Jae Sung, Morales, Liza D., Hernandez, Joselin, Mummidi, Srinivas, Williams-Blangero, Sarah, Jang, Ik-Soon, Tsin, Andrew T., Kim, Dae Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023867/
https://www.ncbi.nlm.nih.gov/pubmed/29955047
http://dx.doi.org/10.1038/s41419-018-0781-9

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