The role of sentrin-specific protease 2 substrate recognition in TGF-β-induced tumorigenesis

Smad4, a common-mediator of Smads, plays a central role in forming complexes with receptor-phosphorylated Smads, and then transduces transforming growth factor (TGF)-β signals into the nuclei. Although many cellular factors are involved in TGF-β induced epithelial-to-mesenchymal transition (EMT) and...

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Detalles Bibliográficos
Autores principales: Chang, Che-Chang, Huang, Yen-Sung, Lin, Ying-Mei, Lin, Chia-Ju, Jeng, Jen-Chong, Liu, Shin-Mei, Ho, Tsai-Ling, Chang, Ruei-Ting, Changou, Chun A., Ho, Chun-Chen, Shih, Hsiu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023881/
https://www.ncbi.nlm.nih.gov/pubmed/29955155
http://dx.doi.org/10.1038/s41598-018-28103-8

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