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Global pairwise RNA interaction landscapes reveal core features of protein recognition

RNA–protein interactions permeate biology. Transcription, translation, and splicing all hinge on the recognition of structured RNA elements by RNA-binding proteins. Models of RNA–protein interactions are generally limited to short linear motifs and structures because of the vast sequence sampling re...

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Detalles Bibliográficos
Autores principales: Zhou, Qin, Kunder, Nikesh, De la Paz, José Alberto, Lasley, Alexandra E., Bhat, Vandita D., Morcos, Faruck, Campbell, Zachary T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023938/
https://www.ncbi.nlm.nih.gov/pubmed/29955037
http://dx.doi.org/10.1038/s41467-018-04729-0