Cargando…
Global pairwise RNA interaction landscapes reveal core features of protein recognition
RNA–protein interactions permeate biology. Transcription, translation, and splicing all hinge on the recognition of structured RNA elements by RNA-binding proteins. Models of RNA–protein interactions are generally limited to short linear motifs and structures because of the vast sequence sampling re...
Autores principales: | Zhou, Qin, Kunder, Nikesh, De la Paz, José Alberto, Lasley, Alexandra E., Bhat, Vandita D., Morcos, Faruck, Campbell, Zachary T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023938/ https://www.ncbi.nlm.nih.gov/pubmed/29955037 http://dx.doi.org/10.1038/s41467-018-04729-0 |
Ejemplares similares
-
Latent generative landscapes as maps of functional diversity in protein sequence space
por: Ziegler, Cheyenne, et al.
Publicado: (2023) -
Epistatic contributions promote the unification of incompatible models of neutral molecular evolution
por: de la Paz, Jose Alberto, et al.
Publicado: (2020) -
Information Theory in Molecular Evolution: From Models to Structures and Dynamics
por: Morcos, Faruck
Publicado: (2021) -
Evolutionary entrenchment in immune proteins selects against stabilizing mutations
por: Morcos, Faruck
Publicado: (2022) -
In vivo functional phenotypes from a computational epistatic model of evolution
por: Alvarez, Sophia, et al.
Publicado: (2023)