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Silencing SUMO2 promotes protection against degradation and apoptosis of nucleus pulposus cells through p53 signaling pathway in intervertebral disc degeneration

Objective: Intervertebral disc degeneration (IDD), as a common cause of back pain, is related to the promotion of cellular senescence and reduction in proliferation. Based on recent studies, small ubiquitin-related modifier (SUMO) proteins have been implicated in various biological functions. Theref...

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Detalles Bibliográficos
Autores principales:	Jin, Liu-Zhong, Lu, Ji-Shou, Gao, Jian-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023941/ https://www.ncbi.nlm.nih.gov/pubmed/29700214 http://dx.doi.org/10.1042/BSR20171523

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