Evidence for Shaping of Light Chain Repertoire by Structural Selection

The naïve immunoglobulin (IG) repertoire in the blood differs from the direct output of the rearrangement process. These differences stem from selection that affects the germline gene usage and the junctional nucleotides. A major complication obscuring the details of the selection mechanism in the h...

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Detalles Bibliográficos
Autores principales: Toledano, Adar, Elhanati, Yuval, Benichou, Jennifer I. C., Walczak, Aleksandra M., Mora, Thierry, Louzoun, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023962/
https://www.ncbi.nlm.nih.gov/pubmed/29988361
http://dx.doi.org/10.3389/fimmu.2018.01307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023962/
https://www.ncbi.nlm.nih.gov/pubmed/29988361
http://dx.doi.org/10.3389/fimmu.2018.01307

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