Cargando…
Retrospective clinical study of multiple keratocystic odontogenic tumors in non-syndromic patients
OBJECTIVES: A keratocystic odontogenic tumor (KOT) is a type of odontogenic tumor that mainly occurs in the posterior mandible. Most KOTs appear as solitary lesions; however, they sometimes occur as multiple cysts. This study analyzed the clinical features of multiple KOTs. MATERIALS AND METHODS: Th...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Oral and Maxillofacial Surgeons
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024063/ https://www.ncbi.nlm.nih.gov/pubmed/29963491 http://dx.doi.org/10.5125/jkaoms.2018.44.3.107 |
_version_ | 1783335986793545728 |
---|---|
author | Hwang, Dae-Seok Kim, Yun-Ho Kim, Uk-Kyu Ryu, Mi-Heon Kim, Gyoo-Cheon |
author_facet | Hwang, Dae-Seok Kim, Yun-Ho Kim, Uk-Kyu Ryu, Mi-Heon Kim, Gyoo-Cheon |
author_sort | Hwang, Dae-Seok |
collection | PubMed |
description | OBJECTIVES: A keratocystic odontogenic tumor (KOT) is a type of odontogenic tumor that mainly occurs in the posterior mandible. Most KOTs appear as solitary lesions; however, they sometimes occur as multiple cysts. This study analyzed the clinical features of multiple KOTs. MATERIALS AND METHODS: The participants were diagnosed with KOT by biopsy with multiple surgical sites, and were patients at the Pusan National University Hospital and the Pusan National University Dental Hospital from January 1, 2005 to March 31, 2016. Charts, records, images and other findings were reviewed. RESULTS: A total of 31 operations were conducted in 17 patients. The mean patient age was 28.4±20.1 years. Multiple KOTs were found to occur at a young age (P<0.01). The predominant sites were in the posterior mandible (28.6%). Most cases of multiple lesions appeared in both the upper and lower jaw, and 40.3% of lesions were associated with unerupted and impacted teeth. The overall recurrence rate measured by operation site was 10.4% (8/77 sites). No patients were associated with nevoid basal cell carcinoma syndrome. CONCLUSION: The pure recurrence rate was lower than estimated, but there was a higher possibility of secondary lesions regardless of the previous operation site; therefore, long-term follow-up is necessary. |
format | Online Article Text |
id | pubmed-6024063 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Korean Association of Oral and Maxillofacial Surgeons |
record_format | MEDLINE/PubMed |
spelling | pubmed-60240632018-06-29 Retrospective clinical study of multiple keratocystic odontogenic tumors in non-syndromic patients Hwang, Dae-Seok Kim, Yun-Ho Kim, Uk-Kyu Ryu, Mi-Heon Kim, Gyoo-Cheon J Korean Assoc Oral Maxillofac Surg Original Article OBJECTIVES: A keratocystic odontogenic tumor (KOT) is a type of odontogenic tumor that mainly occurs in the posterior mandible. Most KOTs appear as solitary lesions; however, they sometimes occur as multiple cysts. This study analyzed the clinical features of multiple KOTs. MATERIALS AND METHODS: The participants were diagnosed with KOT by biopsy with multiple surgical sites, and were patients at the Pusan National University Hospital and the Pusan National University Dental Hospital from January 1, 2005 to March 31, 2016. Charts, records, images and other findings were reviewed. RESULTS: A total of 31 operations were conducted in 17 patients. The mean patient age was 28.4±20.1 years. Multiple KOTs were found to occur at a young age (P<0.01). The predominant sites were in the posterior mandible (28.6%). Most cases of multiple lesions appeared in both the upper and lower jaw, and 40.3% of lesions were associated with unerupted and impacted teeth. The overall recurrence rate measured by operation site was 10.4% (8/77 sites). No patients were associated with nevoid basal cell carcinoma syndrome. CONCLUSION: The pure recurrence rate was lower than estimated, but there was a higher possibility of secondary lesions regardless of the previous operation site; therefore, long-term follow-up is necessary. The Korean Association of Oral and Maxillofacial Surgeons 2018-06 2018-06-26 /pmc/articles/PMC6024063/ /pubmed/29963491 http://dx.doi.org/10.5125/jkaoms.2018.44.3.107 Text en Copyright © 2018 The Korean Association of Oral and Maxillofacial Surgeons. http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Hwang, Dae-Seok Kim, Yun-Ho Kim, Uk-Kyu Ryu, Mi-Heon Kim, Gyoo-Cheon Retrospective clinical study of multiple keratocystic odontogenic tumors in non-syndromic patients |
title | Retrospective clinical study of multiple keratocystic odontogenic tumors in non-syndromic patients |
title_full | Retrospective clinical study of multiple keratocystic odontogenic tumors in non-syndromic patients |
title_fullStr | Retrospective clinical study of multiple keratocystic odontogenic tumors in non-syndromic patients |
title_full_unstemmed | Retrospective clinical study of multiple keratocystic odontogenic tumors in non-syndromic patients |
title_short | Retrospective clinical study of multiple keratocystic odontogenic tumors in non-syndromic patients |
title_sort | retrospective clinical study of multiple keratocystic odontogenic tumors in non-syndromic patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024063/ https://www.ncbi.nlm.nih.gov/pubmed/29963491 http://dx.doi.org/10.5125/jkaoms.2018.44.3.107 |
work_keys_str_mv | AT hwangdaeseok retrospectiveclinicalstudyofmultiplekeratocysticodontogenictumorsinnonsyndromicpatients AT kimyunho retrospectiveclinicalstudyofmultiplekeratocysticodontogenictumorsinnonsyndromicpatients AT kimukkyu retrospectiveclinicalstudyofmultiplekeratocysticodontogenictumorsinnonsyndromicpatients AT ryumiheon retrospectiveclinicalstudyofmultiplekeratocysticodontogenictumorsinnonsyndromicpatients AT kimgyoocheon retrospectiveclinicalstudyofmultiplekeratocysticodontogenictumorsinnonsyndromicpatients |