A Mechanism for the Activation of the Influenza Virus Transcriptase

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Influenza virus RNA polymerase (FluPol), a heterotrimer composed of PB1, PB2, and PA subunits (P3 in influenza C), performs both transcription and replication of the viral RNA genome. For transcription, FluPol interacts with the C-terminal domain (CTD) of RNA polymerase II (Pol II), which enables Fl...

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Detalles Bibliográficos
Autores principales: Serna Martin, Itziar, Hengrung, Narin, Renner, Max, Sharps, Jane, Martínez-Alonso, Mónica, Masiulis, Simonas, Grimes, Jonathan M., Fodor, Ervin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024077/
https://www.ncbi.nlm.nih.gov/pubmed/29910112
http://dx.doi.org/10.1016/j.molcel.2018.05.011

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