ctDNA and CTCs in Liquid Biopsy – Current Status and Where We Need to Progress

We discuss the current status of liquid biopsy and its advantages and challenges with a focus on pre-analytical sample handling, technologies and workflows. The potential of circulating tumor cells and circulating tumor DNA is pointed out and an overview of corresponding technologies is given.

Detalles Bibliográficos
Autores principales: Neumann, Martin H.D., Bender, Sebastian, Krahn, Thomas, Schlange, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024152/
https://www.ncbi.nlm.nih.gov/pubmed/29977481
http://dx.doi.org/10.1016/j.csbj.2018.05.002
Descripción
Sumario:We discuss the current status of liquid biopsy and its advantages and challenges with a focus on pre-analytical sample handling, technologies and workflows. The potential of circulating tumor cells and circulating tumor DNA is pointed out and an overview of corresponding technologies is given.

Ejemplares similares